HISTOLOGICAL FEATURES OF LYMPHOCYTES, MONOCYTES AND HEMOGLOBIN ONCENTRATIONS IN DOGS WITH MILD AND SEVERE DERMATITIS

Authors

  • Ni Putu Dewi Rahmawati Mahasiswa Sarjana Pendidikan Dokter Hewan, Fakultas Kedokteran Hewan Universitas Udayana, Jl. PB. Sudirman, Denpasar, Bali, Indonesia, 80234
  • Ni Ketut Suwiti Laboratorium Histologi Veteriner, Fakultas Kedokteran Hewan, Universitas Udayana, Jl. PB. Sudirman Denpasar, Bali, Indonesia
  • Sri Kayati Widyastuti Laboratorium Ilmu Penyakit Dalam Veteriner, Fakultas Kedokteran Hewan Universitas Udayana, Jl. Raya Sesetan Gg. Markisa No. 6, Denpasar Selatan, Bali, Indonesia
  • Nyoman Sadra Dharmawan Laboratorium Diagnosis Klinik, Patologi Klinik dan Ragiologi Veteriner, Fakultas Kedokteran Hewan, Universitas Udayana, Jl. PB. Sudirman, Denpasar, Bali, Indonesia, 80234
  • Ni Luh Eka Setiasih Laboratorium Histologi Veteriner, Fakultas Kedokteran Hewan Universitas Udayana, Jl. PB. Sudirman, Denpasar, Bali, Indonesia 80234
  • I Made Kardena Laboratorium Patologi Veteriner, Fakultas Kedokteran Hewan, Universitas Udayana, Jl. PB. Sudirman, Denpasar, Bali, Indonesia

DOI:

https://doi.org/10.24843/bulvet.2025.v17.i03.p30

Keywords:

dog, dermatitis, lymphocytes, monocytes, necrosis, hemoglobin

Abstract

Dogs are susceptible to various dermatological disorders, among which dermatitis is commonly observed. This condition may be caused by fungal infections, ectoparasites, bacterial agents, or metabolic disorders. Dermatitis presents with clinical manifestations ranging from mild to severe, often characterized by widespread skin lesions. The associated inflammatory response may induce alterations in the immune system, particularly affecting agranulocytic leukocytes namely lymphocytes and monocytes or leading to cellular necrosis. Severe dermatitis is frequently accompanied by secondary infections, which may elevate the risk of inflammation-induced anemia and result in changes to hemoglobin (HGB) levels. This study aims to investigate the histological features of necrotic lymphocytes and monocytes, as well as hemoglobin (HGB) levels, in dogs affected by mild and severe dermatitis. Histological examination revealed that necrotic lymphocytes and monocytes exhibited signs of pyknosis, karyorrhexis, and karyolysis. The number of necrotic lymphocytes in dogs with mild dermatitis (10±4.64) was slightly higher than in those with severe dermatitis (8.65±3.38), although the difference was not statistically significant (P˃0.05). In contrast, the number of necrotic monocytes in mild dermatitis cases (19.3±20.8) was significantly greater than in severe cases (3.35±11.62) (P˂0.05). Hemoglobin levels in dogs with mild dermatitis (10.75±4.23) were marginally lower than those in severe cases (11.23±2.9), with no statistically significant difference (P˃0.05).

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Published

2025-06-04